Chemotherapy Drugs
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CHEMOTHERAPY DRUGS

Chemotherapy Drugs are commonly known as anti-cancer drugs.

 

Types of chemotherapy drugs are dependent of many factors such as:

Types, Usage, Company & Brands

  1. Alka lytic agents: There are several types of alkylating agents used in chemotherapy treatments such as

a) Mustard gas derivative

  1. Mechlorethamine:  It is also known as mustine, nitrogen mustard, and HN2, is the prototype anticancer chemotherapy drug.

Brand Strength Company Availability
MUSTRAGEN     NA
VALCHLOR     NA
       

  1. Cyclophosphamide: It is also known as cytophosphane among other names, is a medication used as chemotherapy drugs and to suppress the immune system.

Brand Strength Company Availability
ENDOXAN 500 mg Inj Baxter Yes
CYCLOCEL 500 mg Inj Celon Yes
PHOSMID 500 mg Inj Neon Yes

  1. Chlorambucil: This medication is used to treat certain types of cancer (such as leukemia, lymphoma).

Brand Strength Company Availability
CELKERAN 5 mg Tab Celon Yes
CLOKERAN 5 mg Tab Natco Yes
       

  1. Melphalan: Melphalan is used to treat multiple myeloma (a type of cancer of the bone marrow). Melphalan is also used to treat a certain type of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed.

Brand Strength Company Availability
ALKACEL 50 mg Inj Celon Yes
ALPHALAN 5 mg Tab Natco Yes
MEGVAL 50 mg Inj Emcure Yes

  • Ifosfamide:  is used to treat various cancers (such as testicular cancer).

Brand Strength Company Availability
CELOFOS 1 gm & 2 gm Inj Celon Yes
FOSFA 1 gm & 2 gm Inj Getwell Pharma Yes
IPAMIDE 1 gm & 2 gm Inj Fresinius Kabi Yes

b) Ethylenimines: These are derived from ethylenimine, which is a three-pointed ring of two carbon atoms and a nitrogen atom. Ethylenimine is also called aziridine.

i) Thiotepa: Thiotepa is used to treat the bladder to treat bladder cancer. Thiotepa is also used with other medications to prevent rejection of a stem cell transplant.

Brand Strength Company Availability
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ii) Hexamethylmelamine:  It is used as a second line agent in ovarian cancer.

Brand Strength Company Availability
      N/A
      N/A
      N/A

c) Alkylsulfonates:  Alkyl sulfonates are commonly used for the separation of water-soluble basic analytes.

  1. Busulfan: Busulfan is chemotherapy drugs in use since 1959. It is a cell cycle non-specific alkylating antineoplastic.

Brand Strength Company Availability
BUCELON 60 mg Inj & 2 mg Tab Celon Yes
BUFATAS 60 mg Inj Intas Yes
EMSULFAN 60 mg Inj Emcure Yes

d) Hydrazine and Triazines: It is used as an antioxidant, an oxygen scavenger.

  1. Altretamine: It is used to treat cancer of the ovaries.

Brand Strength Company Availability
      N/A
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  1. Procarbazine: Procarbazine is used in combination with other medications to treat certain types of Hodgkins disease (types of cancer that begin in a type of WBC that normally fights infection).

Brand Strength Company Availability
HODPRO 50 mg Capsule Neon Yes
       
       

  1. Dacarbazine: Dacarbazine is used to treat certain types of cancer, such as skin cancer and Hodgkin’s disease.

Brand Strength Company Availability
CELDAZ 200 mg Inj Celon Yes
DABAZ 200 mg Inj Intas Yes
DACAREX 200 mg Inj Alkem Yes

  1. Temozolomide: It is used to treat certain types of brain tumours.

Brand Strength Company Availability
GLIOZ 100 mg Cap Dr. Reddy’s Yes
TEMONAT 100 mg Cap Natco Yes
NUBLAST 100 mg Cap Zydus Cadila Yes

  • Nitrosureas:  A group of cancer drugs called alkylating agents because they act by the process of alkylation to inhibit DNA repair. The nitrosoureas can cross the blood-brain barrier and are used to treat brain tumours.
  • Carmustine: This medication is used to treat certain types of cancer (including multiple myeloma, brain tumor, Hodgkin’s disease, non-Hodgkin’s lymphoma).

Brand Strength Company Availability
CONSIUM 100 mg Inj Emcure Yes
CARMUTHER 100 mg Inj Therdose Pharma Yes
NITSUM 100 mg Inj Celon Yes

  • Lomustine: Lomustine is used to treat certain types of brain tumours.

Brand Strength Company Availability
MOOSTIN 40 mg Cap Miracalus Pharma Yes
LOMAT 40 mg Cap Neon Yes
LOMTIN 40 mg Cap Dr. Reddy’s Yes

  • Streptozocin:  treating metastatic cancer of the pancreatic islet cells.

Brand Strength Company Availability
      N/A
      N/A
      N/A

  • Metal salts:
  • Carboplatin: It is used to treat ovarian cancer.it is also used for other types of cancer, including lung, head and neck, endometrial, esophageal, bladder, breast, and cervical; central nervous system or germ cell tumors; osteogenic sarcoma.

Brand Strength Company Availability
CARBOPLATIN 450 mg & 150 mg Inj Pfizer Yes
KEMOCARB 450 mg & 150 mg Inj Fresinius Kabi Yes
STRICARB 450 mg & 150 mg Inj Mylan Yes

  1.  Cisplatin: Treatment of  bladder cancer,metastatic ovarian cancer, and metastatic testicular cancer. Testicular, ovarian, bladder, head and neck, esophageal, small and non-small cell lung, breast, cervical, stomach and prostate cancers.

Brand Strength Company Availability
KEMOPLAT 50 mg & 10 mg Inj Fresinius Kabi Yes
CELPLAT 50 mg & 10 mg Inj Celon Yes
STRITIN 50 mg & 10 mg Inj Mylan Yes

  1. Oxaliplatin: to treat advanced cancer of the colon and rectum.

Brand Strength Company Availability
OXITAN 100 mg & 50 mg Infusion Fresinius Kabi Yes
CELDACH 100 mg & 50 mg Infusion Celon Yes
DACOTIN 100 mg & 50 mg Infusion Dr. Reddy’s Yes

  •  Plant alkaloids: They are from certain types of plants. The plant alkaloids are cell-cycle specific.  This means they attack the cells during various phases of division.
  • Vinca alkaloids: It is made from the periwinkle plant .

Vincristine,

Brand Strength Company Availability
BIOCRISTIN AQ 1 mg Inj Biochem Yes
VINLON 1 mg Inj Celon Yes
CYTOCRISTIN 1 mg Inj Cipla Yes

Vinblastine

Brand Strength company Availability
CHEMOBLAST 10 mg Inj Neon Yes
CYTOBLASTIN 10 mg Inj Cipla Yes
VBLASTIN 10 mg Inj Chandra Bhagat Pharma Yes

Vinorelbine.

Brand Strength Company Availability
VINELBINE 10 mg & 50 mg Inj Fresinius Kabi Yes
NEOBEN 10 mg & 50 mg Inj Neon Yes
ZORELBIN 10 mg & 50 mg Inj Alkem Yes

ii) Taxanes: It is made from the bark of the Pacific Yew tree .  They are also known as antimicrotubule agents.

   Paclitaxel

Brand Strength Company Availability
INTAXEL 100 mg Fresinius Kabi Yes
ABRAXANE 100 mg Biocon Yes
CELTAX 100 mg Celon Yes

  Docetaxel

Brand Strength Company Availability
DAXOTEL 80 mg & 120 mg Fresinius Kabi Yes
DOCETERO 80 mg & 120 mg Hetero Drugs Yes
TAXOTERE 80 mg & 120 mg Emcure Yes

  1. Podophyllotoxins: They are derived from the May apple plant.

Brand Strength Company Availability
ETOLON 100 mg Inj Celon Yes
       
       

  • Tenisopide

Brand Strength Company Availability
      N/A
      N/A
      N/A

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  1. Camptothecan analogs are derived from the Asian “Happy Tree” (Camptotheca acuminata), also known as topoisomerase inhibitors, used in certain types of chemotherapy. 
  2. Irinotecan

Brand Strength Company Availability
IRINOTEL 40 mg & 100 mg Fresinius Kabi Yes
       
       

  • Topotecan.

Brand Strength Company Availability
      N/A
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